GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| UVM | cis | rs12971120 | 1 | rs2278161 | chr18:72176083 | CNDP2 | chr18:72163597-72188356:+ | 0.72 | 5.41 | 1.41E-6 | Refractive error |
| UVM | cis | rs12971120 | 1 | rs2278162 | chr18:72175814 | CNDP2 | chr18:72163597-72188356:+ | 0.72 | 5.41 | 1.41E-6 | Refractive error |
| UVM | cis | rs9876781 | 1 | rs2279077 | chr3:48474249 | TREX1 | chr3:48501186-48509043:+ | -0.39 | -5.04 | 5.32E-6 | Longevity |
| UVM | cis | rs2071518 | 1 | rs2279112 | chr8:120429024 | NOV | chr8:120428552-120436678:+ | 0.59 | 4.89 | 9.01E-6 | Blood pressure |
| UVM | cis | rs9876781 | 1 | rs2290822 | chr3:48473204 | TREX1 | chr3:48501186-48509043:+ | -0.4 | -5.1 | 4.38E-6 | Longevity |
| UVM | cis | rs11190604 | 1 | rs2295770 | chr10:102239829 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295772 | chr10:102265183 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295773 | chr10:102265815 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295774 | chr10:102265847 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295776 | chr10:102295629 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295779 | chr10:102296061 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2295780 | chr10:102305965 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.1 | 4.38E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2298074 | chr10:102247526 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs11190604 | 1 | rs2298075 | chr10:102247408 | SEC31B | chr10:102246403-102289636:- | -0.39 | -5.11 | 4.24E-6 | Palmitoleic acid (16:1n-7) plasma levels |
| UVM | cis | rs10242455 | 1 | rs2301889 | chr7:98931105 | PTCD1 | chr7:99016751-99063808:- | 0.7 | 4.85 | 1.07E-5 | Blood metabolite levels |